CMRF35-Like Molecule (CD300C2) protein (Fc Tag)

Catalog No. ABIN7318733

This Recombinant CMRF35-Like Molecule protein is expressed in Human Cells.

Quick Overview for CMRF35-Like Molecule (CD300C2) protein (Fc Tag) (ABIN7318733)

Target: CMRF35-Like Molecule (CD300C2)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: Fc Tag

Purpose: Recombinant Human LMIR2/CD300C Protein (Fc Tag)

Sequence: Gly21-Arg183

Characteristics: Recombinant Human Leukocyte Mono Ig-like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gly21-Arg183 is expressed with a Fc tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CMRF35-Like Molecule (CD300C2)

Alternative Name: LMIR2/CD300C

Background:

Background: CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

Synonym: CMRF35-Like Molecule 6, CLM-6, CD300 Antigen-Like Family Member C, CMRF35-A1, CMRF-35, Immunoglobulin Superfamily Member 16, IgSF16, CD300c, CD300C, CMRF35, CMRF35A, CMRF35A1, IGSF16

Molecular Weight: 44.9 kDa

UniProt: Q08708