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CTGF Protein

This Recombinant CTGF protein is expressed in Human Cells.
Catalog No. ABIN7318333
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Quick Overview for CTGF Protein (ABIN7318333)

Target

See all CTGF Proteins
CTGF (Connective Tissue Growth Factor (CTGF))

Protein Type

Recombinant

Origin

  • 22
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Source

  • 32
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human CTGF/CCN2 Protein

    Sequence

    Glu27-Ala180

    Characteristics

    Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Glu27-Ala180 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CTGF (Connective Tissue Growth Factor (CTGF))

    Alternative Name

    CTGF/CCN2

    Background

    Background: CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).

    Synonym: Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8

    Molecular Weight

    16.3 kDa

    UniProt

    P29279

    Pathways

    Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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