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CTGF Protein

This Recombinant CTGF protein is expressed in Human Cells.
Catalog No. ABIN7318333

Quick Overview for CTGF Protein (ABIN7318333)

Target

See all CTGF Proteins
CTGF (Connective Tissue Growth Factor (CTGF))

Protein Type

Recombinant

Origin

  • 24
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Source

  • 32
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human CTGF/CCN2 Protein

    Sequence

    Glu27-Ala180

    Characteristics

    Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Glu27-Ala180 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CTGF (Connective Tissue Growth Factor (CTGF))

    Alternative Name

    CTGF/CCN2

    Background

    Background: CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).

    Synonym: Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8

    Molecular Weight

    16.3 kDa

    UniProt

    P29279

    Pathways

    Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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