DMP1 Protein (His tag)
Quick Overview for DMP1 Protein (His tag) (ABIN7318398)
Target
See all DMP1 (DMTF1) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This DMP1 protein is labelled with His tag.
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Purpose
- Recombinant Human DMP1 Protein (His Tag)
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Sequence
- Lys17-Tyr513
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Characteristics
- Recombinant Human Dentin matrix protein 1 is produced by our Mammalian expression system and the target gene encoding Lys17-Tyr513 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 1-761) protein (His tag)
custom-made DMTF1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 1-760) protein (His tag)custom-made DMTF1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (AA 221-330) protein (GST tag)DMTF1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DMTF1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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Alternative Name
- DMP1
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Background
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Background: Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1).
Synonym: Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1,ARHP,ARHR
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Molecular Weight
- 55.0 kDa
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UniProt
- Q13316
Target
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