PPIB Protein (His tag)

Catalog No. ABIN7319504

Recombinant PPIB protein expressed in Human Cells.

Quick Overview for PPIB Protein (His tag) (ABIN7319504)

Target: PPIB (Cyclophilin B (PPIB))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This PPIB protein is labelled with His tag.

Purpose: Recombinant Human Cyclophilin B/PPIB Protein (His Tag)

Sequence: Asp34-Ala212

Characteristics: Recombinant Human Cyclophilin B is produced by our Mammalian expression system and the target gene encoding Asp34-Ala212 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PPIB (Cyclophilin B (PPIB))

Alternative Name: Cyclophilin B/PPIB

Background:

Background: Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.

Synonym: CYP-S1, CYPB, HEL-S-39, OI9, SCYLP

Molecular Weight: 20.9 kDa

UniProt: P23284