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D Amino Acid Oxidase Protein (His tag)

This Recombinant D Amino Acid Oxidase protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318393

Quick Overview for D Amino Acid Oxidase Protein (His tag) (ABIN7318393)

Target

See all D Amino Acid Oxidase (DAO) Proteins
D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

Protein Type

Recombinant

Origin

  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 10
  • 4
  • 2
  • 2
Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This D Amino Acid Oxidase protein is labelled with His tag.

    Purpose

    Recombinant Human D-Amino-Acid Oxidase/DAO Protein (His Tag)

    Sequence

    Met 1-Leu347

    Characteristics

    Recombinant Human D-Amino-Acid Oxidase is produced by our E.coli expression system and the target gene encoding Met1-Leu347 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, 2 mM EDTA, pH 8.0 .

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))

    Alternative Name

    D-Amino-Acid Oxidase/DAO

    Background

    Background: D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups.

    Synonym: D-Amino-Acid Oxidase, DAAO, DAMOX, DAO

    Molecular Weight

    41.6 kDa

    UniProt

    P14920
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