D Amino Acid Oxidase Protein (AA 1-347, full length) (His-SUMO Tag)
Quick Overview for D Amino Acid Oxidase Protein (AA 1-347, full length) (His-SUMO Tag) (ABIN5709381)
Target
See all D Amino Acid Oxidase (DAO) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- full length, AA 1-347
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Purification tag / Conjugate
- This D Amino Acid Oxidase protein is labelled with His-SUMO Tag.
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Sequence
- MRVVVIGAGV IGLSTALCIH ERYHSVLQPL DIKVYADRFT PLTTTDVAAG LWQPYLSDPN NPQEADWSQQ TFDYLLSHVH SPNAENLGLF LISGYNLFHE AIPDPSWKDT VLGFRKLTPR ELDMFPDYGY GWFHTSLILE GKNYLQWLTE RLTERGVKFF QRKVESFEEV AREGADVIVN CTGVWAGALQ RDPLLQPGRG QIMKVDAPWM KHFILTHDPE RGIYNSPYII PGTQTVTLGG IFQLGNWSEL NNIQDHNTIW EGCCRLEPTL KNARIIGERT GFRPVRPQIR LEREQLRTGP SNTEVIHNYG HGGYGLTIHW GCALEAAKLF GRILEEKKLS RMPPSHL
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Purification
- SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- D Amino Acid Oxidase (DAO) (D-Amino-Acid Oxidase (DAO))
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Alternative Name
- OXDA
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Background
- Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which roves D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
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Molecular Weight
- 55.45 kDa
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UniProt
- P14920
Target
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