DEFB104A Protein

Catalog No. ABIN7319216

This Recombinant DEFB104A protein is expressed in Escherichia coli (E. coli).

Quick Overview for DEFB104A Protein (ABIN7319216)

Target: DEFB104A (Defensin, beta 104A (DEFB104A))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human DEFB104A Protein

Sequence: Glu23-Pro72

Characteristics: Recombinant Human beta-Defensin 4 is produced by our E.coli expression system and the target gene encoding Glu23-Pro72 is expressed.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 130 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: DEFB104A (Defensin, beta 104A (DEFB104A))

Alternative Name: DEFB104A

Background:

Background: Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, they are released by proteolytic cleavage of a signal sequence.

Synonym: Beta-Defensin 104, Beta-Defensin 4, BD-4, DEFB-4, hBD-4, Defensin Beta 104, DEFB104A, DEFB104, DEFB4, DEFB104B

Molecular Weight: 6.0 kDa

UniProt: Q8WTQ1