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Desmin Protein (DES) (His tag)

This Recombinant Desmin protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318402

Quick Overview for Desmin Protein (DES) (His tag) (ABIN7318402)

Target

See all Desmin (DES) Proteins
Desmin (DES)

Protein Type

Recombinant

Origin

  • 10
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 10
  • 7
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Desmin protein is labelled with His tag.

    Purpose

    Recombinant Human Desmin Protein (His Tag)

    Sequence

    Val260-Leu470

    Characteristics

    Recombinant Human Desmin is produced by our E.coli expression system and the target gene encoding Val260-Leu470 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Desmin (DES)

    Alternative Name

    Desmin

    Background

    Background: Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.

    Synonym: Desmin, DES

    Molecular Weight

    26.7 kDa

    UniProt

    P17661
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