Desmin Protein (DES) (His tag)
Quick Overview for Desmin Protein (DES) (His tag) (ABIN7318402)
Target
See all Desmin (DES) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Desmin protein is labelled with His tag.
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Purpose
- Recombinant Human Desmin Protein (His Tag)
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Sequence
- Val260-Leu470
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Characteristics
- Recombinant Human Desmin is produced by our E.coli expression system and the target gene encoding Val260-Leu470 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Desmin (DES)
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Alternative Name
- Desmin
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Background
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Background: Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
Synonym: Desmin, DES
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Molecular Weight
- 26.7 kDa
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UniProt
- P17661
Target
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