DKK3 Protein (His tag)
Quick Overview for DKK3 Protein (His tag) (ABIN7318405)
Target
Protein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This DKK3 protein is labelled with His tag.
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Purpose
- Recombinant Human DKK3 Protein (His Tag)
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Sequence
- Ala22-Ile350
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Characteristics
- Recombinant Human Dickkopf-Related Protein 3 is produced by our Mammalian expression system and the target gene encoding Ala22-Ile350 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- DKK3
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Background
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Background: Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine-rich domains that are separated by a 12 amino acid linker region. Dkk-3 also have one prokineticin domain. DKK3 is involved in embryonic development through its inhibition of the WNT signaling pathway. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear.
Synonym: Dickkopf-Related Protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, REIC
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Molecular Weight
- 37.2 kDa
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UniProt
- Q9UBP4
Target
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