ENTPD2 Protein (AA 29-460) (His tag)
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- Target See all ENTPD2 Proteins
- ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 29-460
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This ENTPD2 protein is labelled with His tag.
- Purpose
- Recombinant Human NTPDase 2/ENTPD2 Protein (aa 29-460, His Tag)(Active)
- Sequence
- Thr 29-Asp460
- Characteristics
- A DNA sequence encoding the mature form of human ENTPD2 (Q9Y5L3) (Thr29-Asp460) was expressed, with a polyhistidine tag at the N-terminus.
- Purity
- > 85 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to hydrolyze the 5'phosphate groups from the substrate adenosine 5'triphosphate(ATP).The specific activity is > 5,000 pmoles/min/μg.
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- Discover our top product ENTPD2 Protein
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Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2) (AA 1-495) protein (His tag)
custom-made ENTPD2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2) (AA 1-495) protein (His tag)custom-made ENTPD2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2) proteinENTPD2 Origin: Human Host: HEK-293 Cells Synthetic Nanodisc
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
- Alternative Name
- NTPDase 2/ENTPD2 (ENTPD2 Products)
- Background
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Background: NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii infection. In L. pneumophila it was demonstrated that an E-NTPDase, similar to CD39, is essential for intracellular bacterial multiplication. NTPDase 2 is an integral membrane protein. In the nervous system, it could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Alternative splicing of NTPDase 2 gene results in multiple transcript variants.
Synonym: CD39L1;NTPDase-2;RP11-229P13.11-001
- Molecular Weight
- 49.3 kDa
- UniProt
- Q9Y5L3
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