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ENTPD2 Protein (His tag)

MALS verified ENTPD2 Origin: Mouse Host: CHO Cells Recombinant 95 % Active
Catalog No. ABIN7488921
  • Target See all ENTPD2 Proteins
    ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 6
    • 4
    • 1
    • 1
    Mouse
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Purification tag / Conjugate
    This ENTPD2 protein is labelled with His tag.
    Purpose
    Mouse CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)
    Sequence
    Cys 26 - Ser 462
    Characteristics
    Mouse CD39L1 / ENTPD2 Protein, His Tag is expressed from CHO cells. It contains AA Cys 26 - Ser 462 (Accession # O55026-1).
    Purity
    95 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
    Top Product
    Discover our top product ENTPD2 Protein
  • Comment

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 50.2 kDa. The protein migrates as 44-46 kDa and 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    20 mM Tris,150 mM NaCl, pH 7.5
    Storage
    -80 °C
    Storage Comment
    -70°C
  • Target
    ENTPD2 (Ectonucleoside Triphosphate diphosphohydrolase 2 (ENTPD2))
    Alternative Name
    CD39L1 (ENTPD2 Products)
    Synonyms
    MGC76207 Protein, MGC151796 Protein, CD39L1 Protein, NTPDase-2 Protein, Cd39l1 Protein, NTPDase2 Protein, ectonucleoside triphosphate diphosphohydrolase 2 Protein, Ectonucleoside triphosphate diphosphohydrolase 2 Protein, entpd2 Protein, ENTPD2 Protein, enp2 Protein, Entpd2 Protein
    Background
    CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.
    Molecular Weight
    50.2 kDa
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