FANCA Protein (His tag)
Quick Overview for FANCA Protein (His tag) (ABIN7317446)
Target
See all FANCA ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This FANCA protein is labelled with His tag.
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Purpose
- Recombinant Human FANCA/FACA Protein (His Tag)
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Sequence
- Met 1-Cys 297
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Characteristics
- A DNA sequence encoding the human FANCA (AAH08979.1) (Met 1-Cys 297) was expressed, with a polyhistidine tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Fanconi Anemia Group A Protein (FANCA) (AA 1-1455) protein (His tag)
custom-made FANCA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fanconi Anemia Group A Protein (FANCA) (AA 1-1439) protein (His tag)custom-made FANCA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fanconi Anemia Group A Protein (FANCA) (AA 1-297) protein (GST tag)FANCA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile 20 mM Tris, 200 mM NaCl, pH 8.5, 20 % glycerol, 0.1 % Triton, 1 mM TCEP
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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Alternative Name
- FANCA/FACA
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Background
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Background: FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2.
Synonym: FA;FA-H;FA1;FAA;FACA;FAH;FANCH
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Molecular Weight
- 35.2 kDa
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Pathways
- DNA Damage Repair
Target
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