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GGCT Protein (His tag)

This Recombinant GGCT protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7319225

Quick Overview for GGCT Protein (His tag) (ABIN7319225)

Target

See all GGCT Proteins
GGCT (gamma-Glutamylcyclotransferase (GGCT))

Protein Type

Recombinant

Origin

  • 6
  • 2
  • 1
Human

Source

  • 3
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This GGCT protein is labelled with His tag.

    Purpose

    Recombinant Human GGCT Protein (His Tag)

    Sequence

    Met 1-Leu188

    Characteristics

    Recombinant Human gamma-Glutamylcyclotransferase is produced by our E.coli expression system and the target gene encoding Met1-Leu188 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    GGCT (gamma-Glutamylcyclotransferase (GGCT))

    Alternative Name

    GGCT

    Background

    Background: Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.

    Synonym: Gamma-Glutamylcyclotransferase, Cytochrome C-Releasing Factor 21, GGCT, C7orf24, CRF21

    Molecular Weight

    23.2 kDa

    UniProt

    O75223
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