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CXCL9 Protein

This Recombinant CXCL9 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7320505

Quick Overview for CXCL9 Protein (ABIN7320505)

Target

See all CXCL9 Proteins
CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

Protein Type

Recombinant

Origin

  • 11
  • 5
  • 1
  • 1
Mouse

Source

  • 10
  • 4
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by SDS-PAGE
  • Purpose

    Recombinant Mouse CXCL9 Protein

    Sequence

    Thr22-Thr126

    Characteristics

    Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Thr22-Thr126 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

    Alternative Name

    CXCL9

    Background

    Background: Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.

    Synonym: C-X-C motif chemokine 9,Cxcl9,Gamma-interferon-induced monokine,Monokine induced by interferon-gamma,MIG,Small-inducible cytokine B9,Scyb9

    Molecular Weight

    12.3 kDa

    UniProt

    P18340
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