Glucagon Protein (GCG) (His tag)
Quick Overview for Glucagon Protein (GCG) (His tag) (ABIN7318536)
Target
See all Glucagon (GCG) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Glucagon protein is labelled with His tag.
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Purpose
- Recombinant Human Glucagon/GCG Protein (His Tag)
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Sequence
- Arg21-Lys180
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Characteristics
- Recombinant Human Glucagon is produced by our Mammalian expression system and the target gene encoding Arg21-Lys180 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Glucagon (GCG) (AA 90-180) protein (His-IF2DI Tag)
GCG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Glucagon (GCG) (AA 21-180) protein (His-IF2DI Tag)GCG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Glucagon (GCG) (AA 53-89) protein (His-IF2DI Tag)GCG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Glucagon (GCG) (AA 1-180) protein (GST tag)GCG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Glucagon (GCG) (AA 90-180) protein (His tag)GCG Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,200 mM NaCl,1 mM DTT,50 % Glycerol, pH 8.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Glucagon (GCG)
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Alternative Name
- Glucagon/GCG
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Background
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Background: Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. In the glucagon antagonist, His-53 and Phe-58 are missing. This antagonist has been successfully utilized to reduce glucose concentration in vivo.
Synonym: Glucagon, Glicentin, Glicentin-Related Polypeptide, GRPP, Oxyntomodulin, OXM, OXY, Glucagon, Glucagon-Like Peptide 1, GLP-1, Incretin Hormone, Glucagon-like Peptide 1, GLP-1, Glucagon-Like Peptide 2, GLP-2, GCG
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Molecular Weight
- 18.6 kDa
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UniProt
- P01275
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
Target
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