Glucagon Protein (GCG) (AA 90-180) (His tag)
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- Target See all Glucagon (GCG) Proteins
- Glucagon (GCG)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 90-180
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Glucagon protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GCG, 90-180aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product GCG Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.2M NaCl
- Storage
- 4 °C
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- Target
- Glucagon (GCG)
- Alternative Name
- GCG (GCG Products)
- Synonyms
- GLP1 Protein, GLP2 Protein, GRPP Protein, GLP-1 Protein, Glu Protein, PPG Protein, GCG Protein, gcg-A Protein, gcg1 Protein, glucagon Protein, glucagon L homeolog Protein, GCG Protein, Gcg Protein, gcg.L Protein
- Background
- Glucagon, also known as GCG, a hormone secreted by the pancreas, raises blood glucose levels. Its effect is opposite that of insulin, which lowers blood glucose levels. The pancreas releases glucagon when blood sugar (glucose) levels fall too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. Glucagon also stimulates the release of insulin, so glucose can be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels at a stable level. Recombinant human GCG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Glucagon, GLP1, GLP2, GRPP. NCBI no.: NP_002045
- Molecular Weight
- 12.8 kDa (112aa), confirmed by MALDI-TOF
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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