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Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag)

Recombinant Glucose-6-Phosphate Dehydrogenase protein expressed in Human Cells.
Catalog No. ABIN7318537

Quick Overview for Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag) (ABIN7318537)

Target

See all Glucose-6-Phosphate Dehydrogenase (G6PD) Proteins
Glucose-6-Phosphate Dehydrogenase (G6PD)

Protein Type

Recombinant

Origin

  • 11
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 11
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Glucose-6-Phosphate Dehydrogenase protein is labelled with His tag.

    Purpose

    Recombinant Human G6PD Protein (His Tag)

    Sequence

    Ala2-Leu515

    Characteristics

    Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Leu515 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    Glucose-6-Phosphate Dehydrogenase (G6PD)

    Alternative Name

    G6PD

    Background

    Background: Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.

    Synonym: Glucose-6-Phosphate 1-Dehydrogenase, G6PD

    Molecular Weight

    60.2 kDa

    UniProt

    P11413

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones
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