Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721523

Product Details

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Glucose-6-Phosphate Dehydrogenase protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human G6PD (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Ai, Dachineni, Kumar, Alfonso, Marimuthu, Bhat: "Aspirin inhibits glucose‑6‑phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites." in: Molecular medicine reports, Vol. 14, Issue 2, pp. 1726-32, (2016) (PubMed).

Target Details

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Alternative Name: g6pd (G6PD Products)

Synonyms: G6PD1 Protein, g6pd Protein, G6pd Protein, G6pdx Protein, g6pdh Protein, g6pd2 Protein, fj78b06 Protein, wu:fj78b06 Protein, si:dkey-90a13.8 Protein, BA3433 Protein, CORTRD1 Protein, G6PDH Protein, GDH Protein, G28A Protein, G6PD Protein, Gpdx Protein, glucose-6-phosphate dehydrogenase Protein, glucose-6-phosphate 1-dehydrogenase Protein, glucose-6-phosphate 1-dehydrogenase (G6PD) Protein, glucose-6-P dehydrogenase Protein, glucose-6-phosphate dehydrogenase L homeolog Protein, glucose-6-phosphate 1-dehydrogenase Zwf Protein, hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Protein, glucose-6-phosphate dehydrogenase X-linked Protein, G6PD Protein, g6pd Protein, g6pD Protein, zwf Protein, LOC100120232 Protein, LACBIDRAFT_188936 Protein, G6pd Protein, g6pd.L Protein, CNG03280 Protein, Tb10.70.5200 Protein, H6PD Protein, G6pdx Protein, H6pd Protein

Background: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 62.3 kDa

NCBI Accession: NP_000393

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones