HPGDS Protein
Quick Overview for HPGDS Protein (ABIN7318567)
Target
See all HPGDS ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human HPGDS/GSTS Protein
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Sequence
- Met 1-Leu199
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Characteristics
- Recombinant Human Hematopoietic Prostaglandin D Synthase is produced by our E.coli expression system and the target gene encoding Met1-Leu199 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 1-199) protein (His tag)
custom-made HPGDS Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 1-199) protein (His tag)custom-made HPGDS Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Hematopoietic Prostaglandin D Synthase (HPGDS) (AA 2-199) protein (His-IF2DI Tag)HPGDS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, pH 7.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))
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Alternative Name
- HPGDS/GSTS
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Background
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Background: Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
Synonym: Hematopoietic Prostaglandin D Synthase, H-PGDS, GST Class-Sigma, Glutathione S-Transferase, Glutathione-Dependent PGD Synthase, Glutathione-Requiring Prostaglandin D Synthase, Prostaglandin-H2 D-Isomerase, HPGDS, GSTS, PGDS, PTGDS2
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Molecular Weight
- 23.6 kDa
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UniProt
- O60760
Target
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