HOXB4 Protein (His tag)
Quick Overview for HOXB4 Protein (His tag) (ABIN7319405)
Target
See all HOXB4 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This HOXB4 protein is labelled with His tag.
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Purpose
- Recombinant Human HOXB4 Protein (His Tag)
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Sequence
- Met1-Leu251
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Characteristics
- Recombinant Human Homeobox protein B4 is produced by our E.coli expression system and the target gene encoding Met1-Leu251 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Homeobox B4 (HOXB4) (AA 1-250) protein (His tag)
custom-made HOXB4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Homeobox B4 (HOXB4) (AA 1-251) protein (His tag)custom-made HOXB4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Homeobox B4 (HOXB4) (AA 1-60) protein (GST tag)HOXB4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Homeobox B4 (HOXB4) (AA 1-251), (full length) protein (His tag)HOXB4 Origin: Human Host: Yeast Recombinant > 90 % SDS
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 4 mM HCl.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- HOXB4 (Homeobox B4 (HOXB4))
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Alternative Name
- HOXB4
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Background
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Background: Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation of stem cells whilst activating the apoptotic pathway in some embryonic structures. The protein HOXB4, as a homeodomain transcription factor, has been shown to be an important regulator of stem cell renewal and hematopoiesis. Incellular or ectopic expression of HOXB4 expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
Synonym: Homeobox protein Hox-B4, Homeobox protein Hox-2.6, Homeobox protein Hox-2F, HOXB4, HOX2F
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Molecular Weight
- 29.8 kDa
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UniProt
- P17483
Target
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