HYAL1 Protein (His tag)
Quick Overview for HYAL1 Protein (His tag) (ABIN7318588)
Target
See all HYAL1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This HYAL1 protein is labelled with His tag.
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Purpose
- Recombinant Human Hyaluronidase-1/HYAL1 Protein (His Tag)
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Sequence
- Phe22-Trp435
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Characteristics
- Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Hyaluronidase-1 (HYAL1) (AA 1-253) protein (GST tag)
HYAL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hyaluronidase-1 (HYAL1) (AA 22-435) protein (His tag)HYAL1 Origin: Human Host: Yeast Recombinant > 90 % SDS
Hyaluronidase-1 (HYAL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HYAL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hyaluronidase-1 (HYAL1) (Transcript Variant 7) protein (Myc-DYKDDDDK Tag)HYAL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- HYAL1 (Hyaluronidase-1 (HYAL1))
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Alternative Name
- Hyaluronidase-1/HYAL1
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Background
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Background: Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
Synonym: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1
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Molecular Weight
- 47.2 kDa
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UniProt
- Q12794
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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