IgG2a Fc protein (Fc Tag)
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- Target
- IgG2a Fc
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- Human Cells
- Purification tag / Conjugate
- Fc Tag
- Purpose
- Recombinant Rat IgG2A Fc/Igg-2a Protein
- Sequence
- Val98-Lys322
- Characteristics
- Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- <1.0 EU per μg as determined by LAL test.
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IgG2a Fc (AA 98-330) protein
Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.5.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IgG2a Fc
- Alternative Name
- IgG2A Fc/Igg-2a
- Background
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Background: Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
Synonym: Ig gamma-2A chain C region, Igg-2a
- Molecular Weight
- 35.2 kDa
- UniProt
- P20760
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