IgG2a Fc protein (Fc Tag)

Catalog No. ABIN7321258

Recombinant protein expressed in Human Cells.

Quick Overview for IgG2a Fc protein (Fc Tag) (ABIN7321258)

Target: IgG2a Fc

Protein Type: Recombinant

Origin: Rat

Source: Human Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: Fc Tag

Purpose: Recombinant Rat IgG2A Fc/Igg-2a Protein

Sequence: Val98-Lys322

Characteristics: Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.

Endotoxin Level: <1.0 EU per μg as determined by LAL test.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.5.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: IgG2a Fc

Alternative Name: IgG2A Fc/Igg-2a

Background:

Background: Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

Synonym: Ig gamma-2A chain C region, Igg-2a

Molecular Weight: 35.2 kDa

UniProt: P20760