Interferon zeta Protein (IFNZ) (His tag)

Catalog No. ABIN7320569

Recombinant Interferon zeta protein expressed in Human Cells.

Quick Overview for Interferon zeta Protein (IFNZ) (His tag) (ABIN7320569)

Target: Interferon zeta (IFNZ)

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This Interferon zeta protein is labelled with His tag.

Purpose: Recombinant Mouse IFN-zeta/Limitin Protein (His Tag)

Sequence: Leu22-Arg182

Characteristics: Recombinant Mouse Limitin is produced by our Mammalian expression system and the target gene encoding Leu22-Arg182 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Interferon zeta (IFNZ)

Alternative Name: IFN-zeta/Limitin

Background:

Background: Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30 % sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of MHC class I expression, and the growth inhibition of a myelomonocytic leukemia cell line.

Synonym: Limitin, IFN-z, BGIF, Ifnz, interferon zeta, Lmtn, IFN-zeta

Molecular Weight: 19.5 kDa

UniProt: Q9R1T0