Kallikrein 11 Protein (KLK11) (His tag)

Catalog No. ABIN7319354

This Recombinant Kallikrein 11 protein is expressed in Human Cells.

Quick Overview for Kallikrein 11 Protein (KLK11) (His tag) (ABIN7319354)

Target: Kallikrein 11 (KLK11)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Kallikrein 11 protein is labelled with His tag.

Purpose: Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)

Sequence: Glu19-Asn250

Characteristics: Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Kallikrein 11 (KLK11)

Alternative Name: Kallikrein 11/KLK11

Background:

Background: Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

Synonym: Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP

Molecular Weight: 26.3 kDa

NCBI Accession: NP_006844

Pathways: Complement System