Lactoferrin Protein (His tag)

Catalog No. ABIN7318710

This Recombinant Lactoferrin protein is expressed in Human Cells.

Quick Overview for Lactoferrin Protein (His tag) (ABIN7318710)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Lactoferrin protein is labelled with His tag.

Purpose: Recombinant Human Lactotransferrin/LTF Protein (His Tag)

Sequence: Gly20-Lys710

Characteristics: Recombinant Human Lactotransferrin/LTF is produced by our Mammalian expression system and the target gene encoding Gly20-Lys710 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Alternative Name: Lactotransferrin/LTF

Background:

Background: Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.

Synonym: Lactotransferrin, Lactoferrin, Talalactoferrin, Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, Lactoferroxin-C, LTF, LF,GIG12,HEL110,HLF2

Molecular Weight: 77.3 kDa

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis