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LYPLA1 Protein (His tag)

This Recombinant LYPLA1 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7318133

Quick Overview for LYPLA1 Protein (His tag) (ABIN7318133)

Target

See all LYPLA1 Proteins
LYPLA1 (Lysophospholipase I (LYPLA1))

Protein Type

Recombinant

Origin

  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 5
  • 4
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This LYPLA1 protein is labelled with His tag.

    Purpose

    Recombinant Human LYPLA1 Protein (His Tag)

    Sequence

    Met 1-Asp230

    Characteristics

    Recombinant Human Acyl-Protein Thioesterase 1 is produced by our E.coli expression system and the target gene encoding Met1-Asp230 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    LYPLA1 (Lysophospholipase I (LYPLA1))

    Alternative Name

    LYPLA1

    Background

    Background: Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1 performs on biological membranes to regulate the multifunctional lysophospholipids. It hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. It hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS, in addition, it also has depalmitoylating activity and low lysophospholipase activity.

    Synonym: Acyl-Protein Thioesterase 1, APT-1, hAPT1, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, LYPLA1, APT1, LPL1

    Molecular Weight

    26.8 kDa

    UniProt

    O75608
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