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MSTN Protein

Recombinant MSTN protein expressed in Human Cells.
Catalog No. ABIN7319794

Quick Overview for MSTN Protein (ABIN7319794)

Target

See all MSTN Proteins
MSTN (Myostatin (MSTN))

Protein Type

Recombinant

Origin

  • 14
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Source

  • 20
  • 18
  • 4
  • 1
  • 1
  • 1
Human Cells

Purity

>95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human/Mouse/Rat GDF-8/Myostatin

    Sequence

    Lys262-Ser375

    Characteristics

    Recombinant Human/Mouse/Rat Growth Differentiation Factor 8 is produced by our Mammalian expression system and the target gene encoding Lys262-Ser375 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    MSTN (Myostatin (MSTN))

    Alternative Name

    GDF-8/Myostatin

    Background

    Background: Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.

    Synonym: Growth/differentiation factor 8, GDF-8, Myostatin, Mstn, Gdf8

    Molecular Weight

    13.1 kDa

    UniProt

    O14793
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