MSTN Protein
Quick Overview for MSTN Protein (ABIN7319794)
Target
See all MSTN ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human/Mouse/Rat GDF-8/Myostatin
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Sequence
- Lys262-Ser375
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Characteristics
- Recombinant Human/Mouse/Rat Growth Differentiation Factor 8 is produced by our Mammalian expression system and the target gene encoding Lys262-Ser375 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- MSTN (Myostatin (MSTN))
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Alternative Name
- GDF-8/Myostatin
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Background
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Background: Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
Synonym: Growth/differentiation factor 8, GDF-8, Myostatin, Mstn, Gdf8
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Molecular Weight
- 13.1 kDa
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UniProt
- O14793
Target
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