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NCALD Protein (His tag)

This Recombinant NCALD protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318816
$474.72
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Quick Overview for NCALD Protein (His tag) (ABIN7318816)

Target

See all NCALD Proteins
NCALD (Neurocalcin delta (NCALD))

Protein Type

Recombinant

Origin

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Human

Source

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Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This NCALD protein is labelled with His tag.

    Purpose

    Recombinant Human Neurocalcin-δ/NCALD Protein (His Tag)

    Sequence

    Met 1-Phe193

    Characteristics

    Recombinant Human Neurocalcin-delta is produced by our E.coli expression system and the target gene encoding Met1-Phe193 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 40 % Glycerol, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    NCALD (Neurocalcin delta (NCALD))

    Alternative Name

    Neurocalcin-delta/NCALD

    Background

    Background: Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.

    Synonym: Neurocalcin-Delta, NCALD

    Molecular Weight

    24.4 kDa

    UniProt

    P61601
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