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Neuroligin 4 Protein (NLGN4) (His tag)

This Recombinant Neuroligin 4 protein is produced in Human Cells.
Catalog No. ABIN7318817

Quick Overview for Neuroligin 4 Protein (NLGN4) (His tag) (ABIN7318817)

Target

See all Neuroligin 4 (NLGN4) Proteins
Neuroligin 4 (NLGN4)

Protein Type

Recombinant

Origin

Human

Source

  • 2
  • 2
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This Neuroligin 4 protein is labelled with His tag.

    Purpose

    Recombinant Human NLGN4X Protein (His Tag)

    Sequence

    Gln42-Ser676

    Characteristics

    Recombinant Human Neuroligin 4, X-Linked is produced by our Mammalian expression system and the target gene encoding Gln42-Ser676 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Neuroligin 4 (NLGN4)

    Alternative Name

    NLGN4X

    Background

    Background: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.

    Synonym: Neuroligin-4 X-Linked, Neuroligin X, HNLX, NLGN4X, KIAA1260, NLGN4

    Molecular Weight

    72.5 kDa

    UniProt

    Q8N0W4

    Pathways

    Cell-Cell Junction Organization, Synaptic Membrane
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