NHP2 Protein (His tag)
Quick Overview for NHP2 Protein (His tag) (ABIN7318843)
Target
See all NHP2 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This NHP2 protein is labelled with His tag.
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Purpose
- Recombinant Human NHP2/NOLA2 Protein (His Tag)
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Sequence
- Met 1-Leu153
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Characteristics
- Recombinant Human Nucleolar protein family A member 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu153 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT, pH 8.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- NHP2 (NHP2 Ribonucleoprotein (NHP2))
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Alternative Name
- NHP2/NOLA2
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Background
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Background: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Synonym: H/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2, NHP2, NOLA2, NHP2P.
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Molecular Weight
- 19.3 kDa
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UniProt
- Q9NX24
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Pathways
- Telomere Maintenance
Target
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