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NHP2 Protein (His tag)

Recombinant NHP2 protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318843

Quick Overview for NHP2 Protein (His tag) (ABIN7318843)

Target

See all NHP2 Proteins
NHP2 (NHP2 Ribonucleoprotein (NHP2))

Protein Type

Recombinant

Origin

  • 5
  • 2
  • 1
  • 1
  • 1
Human

Source

  • 3
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This NHP2 protein is labelled with His tag.

    Purpose

    Recombinant Human NHP2/NOLA2 Protein (His Tag)

    Sequence

    Met 1-Leu153

    Characteristics

    Recombinant Human Nucleolar protein family A member 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu153 is expressed with a 6His tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Conjugate His tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,1 mM DTT, pH 8.0.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    NHP2 (NHP2 Ribonucleoprotein (NHP2))

    Alternative Name

    NHP2/NOLA2

    Background

    Background: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

    Synonym: H/ACA ribonucleoprotein complex subunit 2, Nucleolar protein family A member 2, snoRNP protein NHP2, NHP2, NOLA2, NHP2P.

    Molecular Weight

    19.3 kDa

    UniProt

    Q9NX24

    Pathways

    Telomere Maintenance
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