Quick Overview for NINJ1 Protein (Fc Tag) (ABIN7321087)
Target
See all NINJ1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This NINJ1 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rat Ninjurin-1/NINJ1 Protein (Fc Tag)
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Sequence
- Met 1-Pro 79
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Characteristics
- A DNA sequence encoding the rat NINJ1 (P70617) extracellular domain (Met 1-Pro 79) was fused with the Fc region of human IgG1 at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
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Ninjurin 1 (NINJ1) (AA 1-152) protein (His tag)
custom-made NINJ1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ninjurin 1 (NINJ1) (AA 1-152) protein (His tag)custom-made NINJ1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ninjurin 1 (NINJ1) (AA 1-80) protein (Fc Tag)NINJ1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Ninjurin 1 (NINJ1) (AA 1-152) protein (GST tag)NINJ1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Ninjurin 1 (NINJ1) (AA 1-66) protein (GST tag)NINJ1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NINJ1 (Ninjurin 1 (NINJ1))
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Alternative Name
- Ninjurin-1/NINJ1
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Background
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Background: Ninjurin-1, also known as NINJ1, is a member of the Ninjurin family of transmembrane (TM) proteins. It is expressed in CD19(+) CD10(+) B-cell progenitor cells and higher levels in B-lineage acute lymphoblastic leukemia cells. Ninjurin-1 is expressed also in a number of other adult and embryonic tissues, predominantly in epithelial cells. Its expression is upregulated after axotomy in neurons and in Schwann cells surrounding the distal nerve segment. Upregulated expression of ninjurin-1 has been identified as a marker of minimal residual disease in B-lineage acute lymphoblastic leukemia. It mediates homophilic adhesion, and promotes neurite extension of dorsal root ganglion neurons in vitro. Ninjurin-1 has been found to show a high expression level in the liver tissue of patients with hepatocellular carcinoma, and this seems to be associated with cases of cirrhosis and chronic viral hepatitis. It has been reported that NINJURIN increases p21 expression and induces cellular senescence in human hepatoma cells.
Synonym: NINJ1
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Molecular Weight
- 37 kDa
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UniProt
- P70617
Target
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