NKG2A & CD94 Heterodimer protein (His tag,DYKDDDDK Tag)

Catalog No. ABIN7318830

Recombinant NKG2A & CD94 Heterodimer protein expressed in Human Cells.

Quick Overview for NKG2A & CD94 Heterodimer protein (His tag,DYKDDDDK Tag) (ABIN7318830)

Target: NKG2A & CD94 Heterodimer

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: His tag,DYKDDDDK Tag

Purpose: Recombinant Human NKG2A & CD94 Heterodimer Protein (His & Flag Tag)

Sequence: Arg100-Leu233 & Ser34-Ile179

Characteristics: Recombinant Human Human NKG2A & CD94 Heterodimer is produced by our Mammalian expression system and the target gene encoding Arg100-Leu233 & Ser34-Ile179 is expressed with a 8His, Flag tag at the N-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: NKG2A & CD94 Heterodimer

Background:

Background: NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Can form disulfide-bonded heterodimer with NKG2 family members. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

Synonym: NKG2A&CD94 Heterodimer, KLRC1&CD94 Heterodimer, CD159A&KLRD1 Heterodimer

Molecular Weight: 34.4 kDa