P-Cadherin Protein (CDH3) (Fc Tag)
Quick Overview for P-Cadherin Protein (CDH3) (Fc Tag) (ABIN7320475)
Target
See all P-Cadherin (CDH3) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
 - This P-Cadherin protein is labelled with Fc Tag.
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Purpose
 - Recombinant Mouse Cadherin-3/CDH3 Protein (Fc Tag)
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Sequence
 - Glu100-Gly647
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Characteristics
 - Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
 - < 1.0 EU per μg as determined by the LAL method.
 
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Restrictions
 - For Research Use only
 
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Format
 - Lyophilized
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Reconstitution
 - Please refer to the printed manual for detailed information.
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Buffer
 - Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
 - 4 °C,-20 °C,-80 °C
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Storage Comment
 - Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 
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- P-Cadherin (CDH3)
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Alternative Name
 - Cadherin-3/CDH3
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Background
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Background: Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.
Synonym: Cadherin-3, Placental cadherin, P-cadherin, Cdh3
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Molecular Weight
 - 87.5 kDa
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UniProt
 - P10287
 
Target
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