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P-Cadherin Protein (CDH3) (Fc Tag)

This Recombinant P-Cadherin protein is expressed in Human Cells.
Catalog No. ABIN7320475

Quick Overview for P-Cadherin Protein (CDH3) (Fc Tag) (ABIN7320475)

Target

See all P-Cadherin (CDH3) Proteins
P-Cadherin (CDH3)

Protein Type

Recombinant

Origin

  • 14
  • 6
  • 2
  • 1
Mouse

Source

  • 13
  • 6
  • 2
  • 1
  • 1
Human Cells

Purity

> 90 % as determined by SDS-PAGE
  • Purification tag / Conjugate

    This P-Cadherin protein is labelled with Fc Tag.

    Purpose

    Recombinant Mouse Cadherin-3/CDH3 Protein (Fc Tag)

    Sequence

    Glu100-Gly647

    Characteristics

    Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    P-Cadherin (CDH3)

    Alternative Name

    Cadherin-3/CDH3

    Background

    Background: Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

    Synonym: Cadherin-3, Placental cadherin, P-cadherin, Cdh3

    Molecular Weight

    87.5 kDa

    UniProt

    P10287
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