PPIA Protein
Quick Overview for PPIA Protein (ABIN7319370)
Target
See all PPIA ProteinsProtein Type
Origin
Source
Purity
-
-
Purpose
- Recombinant Human Cyclophilin A Protein
-
Sequence
- Met 1-Glu165
-
Characteristics
- Recombinant Human Peptidyl-prolyl Cis-trans Isomerase A is produced by our E.coli expression system and the target gene encoding Met1-Glu165 is expressed.
-
Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $11,713.77Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $15,754.29Your project requires further customization? Contact us and discover our custom protein solutions
-
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) protein (His tag)
custom-made PPIA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-164) protein (His tag)custom-made PPIA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) protein (GST tag)PPIA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) proteinPPIA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) protein (His tag)PPIA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-164) protein (His tag)PPIA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) proteinPPIA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Frozen, Liquid
-
Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, pH 7.4 .
-
Storage
- -20 °C
-
Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
-
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
-
Alternative Name
- Cyclophilin A
-
Background
-
Background: Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
Synonym: Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A, SP18, PPIA, CYPA
-
Molecular Weight
- 18 kDa
-
UniProt
- P62937
Target
-
