Peroxiredoxin 3 Protein (PRDX3)
Quick Overview for Peroxiredoxin 3 Protein (PRDX3) (ABIN7318890)
Target
See all Peroxiredoxin 3 (PRDX3) ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human Peroxiredoxin-3/PRDX3 Protein
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Sequence
- Pro63-Gln256
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Characteristics
- Recombinant Human Peroxiredoxin-3 is produced by our E.coli expression system and the target gene encoding Pro63-Gln256 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Peroxiredoxin 3 (PRDX3) (AA 63-256) protein (His tag)
PRDX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Peroxiredoxin 3 (PRDX3) (AA 1-256) protein (GST tag)PRDX3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Peroxiredoxin 3 (PRDX3) proteinPRDX3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Peroxiredoxin 3 (PRDX3) proteinPRDX3 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Peroxiredoxin 3 (PRDX3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PRDX3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Peroxiredoxin 3 (PRDX3)
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Alternative Name
- Peroxiredoxin-3/PRDX3
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Background
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Background: Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Synonym: Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
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Molecular Weight
- 21.6 kDa
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UniProt
- P30048
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Target
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