Quick Overview for CD31 Protein (ABIN7197410)
Target
See all CD31 (PECAM1) ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human CD31/PECAM1 Protein
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Sequence
- Met 1-Lys 601
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Characteristics
- The mature form of human CD31 (EAW94208.1) extracellular domain (Met1-Lys 601) with five additional amino acids (DDDDK) at the C-terminus was expressed and purified.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-602) protein (His tag)
PECAM1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet/endothelial Cell Adhesion Molecule (PECAM1) protein (His tag)PECAM1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-150) protein (His tag)PECAM1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-601) (Active) protein (His tag)PECAM1 Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, ELISA, Imm, AcA Active
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 1-738) protein (GST tag)PECAM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) protein (GST tag)PECAM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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Alternative Name
- CD31/PECAM1
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Background
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Background: The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
Synonym: Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1
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Molecular Weight
- 65.1 kDa
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Pathways
- Regulation of Actin Filament Polymerization
Target
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