PIGR Protein (His tag)
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- Target See all PIGR Proteins
- PIGR (Polymeric Immunoglobulin Receptor (PIGR))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PIGR protein is labelled with His tag.
- Purpose
- Recombinant Mouse PIGR Protein (His Tag)(Active)
- Sequence
- Met 1-Lys 645
- Characteristics
- A DNA sequence encoding the extracellular domain (Met 1-Lys 645) of mouse PIGR (NP_035212.2) precursor was expressed with a C-terminal polyhistidine tag.
- Purity
- > 97 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse PIGR at 5 μg/ml (100 μl/well) can bind mouse IgM with a linear range of 0.156-10 μg/ml.
- Top Product
- Discover our top product PIGR Protein
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Polymeric Immunoglobulin Receptor (PIGR) (AA 21-130) protein (GST tag)
PIGR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Polymeric Immunoglobulin Receptor (PIGR) (AA 662-764) protein (His tag)Crystallography grade PIGR Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 669-771) protein (His tag)Crystallography grade PIGR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 19-638) protein (His tag)Crystallography grade PIGR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 19-645) protein (His tag)Crystallography grade PIGR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 19-603) protein (rho-1D4 tag)Crystallography grade PIGR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 19-611) protein (rho-1D4 tag)Crystallography grade PIGR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 19-764) protein (rho-1D4 tag)Crystallography grade PIGR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Polymeric Immunoglobulin Receptor (PIGR) (AA 19-771) protein (rho-1D4 tag)Crystallography grade PIGR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- PIGR (Polymeric Immunoglobulin Receptor (PIGR))
- Alternative Name
- PIGR (PIGR Products)
- Synonyms
- DKFZp469G1013 Protein, RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein
- Background
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Background: Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
Synonym: Pigr
- Molecular Weight
- 70.8 kDa
- NCBI Accession
- NP_035212
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