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PDCD1LG2 Protein (Fc Tag)

Recombinant PDCD1LG2 protein expressed in Human Cells.
Catalog No. ABIN7320964
$345.12
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Quick Overview for PDCD1LG2 Protein (Fc Tag) (ABIN7320964)

Target

See all PDCD1LG2 Proteins
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Protein Type

Recombinant

Origin

  • 25
  • 8
  • 2
  • 2
Cynomolgus

Source

  • 18
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This PDCD1LG2 protein is labelled with Fc Tag.

    Purpose

    Recombinant Cynomolgus PD-L2/B7-DC/CD273 Protein (Fc Tag)

    Sequence

    Leu20-Pro219

    Characteristics

    Recombinant Cynomolgus PD-L2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a Fc tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    Alternative Name

    PD-L2/B7-DC/CD273

    Background

    Background: Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver, it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

    Synonym: Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, Programmed Death Ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2

    Molecular Weight

    49.5 kDa

    UniProt

    A4GW30
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