PROS1 Protein (His tag)

Catalog No. ABIN7197584

Recombinant PROS1 protein expressed in HEK-293 Cells.

Quick Overview for PROS1 Protein (His tag) (ABIN7197584)

Target: PROS1 (PROS) (Protein S (PROS))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This PROS1 protein is labelled with His tag.

Purpose: Recombinant Human PROS1/Protein S Protein (His Tag)

Sequence: Met 1-Ser676

Characteristics: A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PROS1 (PROS) (Protein S (PROS))

Alternative Name: PROS1

Background:

Background: PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

Synonym: PROS,Protein S,PS21,PS22,PS23,PS24,PS25,PSA,THPH5,THPH6

Molecular Weight: 74.1 kDa

UniProt: P07225