REG2 Protein (Fc Tag)

Catalog No. ABIN7320035

This Recombinant REG2 protein is expressed in HEK-293 Cells.

Quick Overview for REG2 Protein (Fc Tag) (ABIN7320035)

Target: REG2 (Regenerating Islet-Derived 2 (REG2))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This REG2 protein is labelled with Fc Tag.

Purpose: Recombinant Mouse REG2/REG-2 Protein (Fc Tag)

Sequence: Met1-Ala173

Characteristics: A DNA sequence encoding the mouse REG2 (NP_033069.1) (Met1-Ala173) was expressed with the Fc region of human IgG1 at the C-terminus.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: REG2 (Regenerating Islet-Derived 2 (REG2))

Alternative Name: REG2/REG-2

Background:

Background: The REG2 Anticoagulation System consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous active control agent, anivamersen. The first-in-human study of the effect of the REG2 Anticoagulation System on thrombin generation demonstrates concentration-dependent suppression of thrombin generation that is reversible without rebound effect, as measured by the CAT assay. Full Name

Synonym: REG2,RegII

Molecular Weight: 43.6 kDa

NCBI Accession: NP_033069