REG2 Protein (Fc Tag)
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- Target See all REG2 Proteins
- REG2 (Regenerating Islet-Derived 2 (REG2))
- Protein Type
- Recombinant
- Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This REG2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Mouse REG2/REG-2 Protein (Fc Tag)
- Sequence
- Met1-Ala173
- Characteristics
- A DNA sequence encoding the mouse REG2 (NP_033069.1) (Met1-Ala173) was expressed with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product REG2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- REG2 (Regenerating Islet-Derived 2 (REG2))
- Alternative Name
- REG2/REG-2 (REG2 Products)
- Synonyms
- RegII Protein, regenerating islet-derived 2 Protein, Reg2 Protein
- Background
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Background: The REG2 Anticoagulation System consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous active control agent, anivamersen. The first-in-human study of the effect of the REG2 Anticoagulation System on thrombin generation demonstrates concentration-dependent suppression of thrombin generation that is reversible without rebound effect, as measured by the CAT assay. Full Name
Synonym: REG2,RegII
- Molecular Weight
- 43.6 kDa
- NCBI Accession
- NP_033069
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