SECTM1A Protein (His tag)

Catalog No. ABIN7320896

This Recombinant SECTM1A protein is expressed in Human Cells.

Quick Overview for SECTM1A Protein (His tag) (ABIN7320896)

Target: SECTM1A (Secreted and Transmembrane 1A (SECTM1A))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: >95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SECTM1A protein is labelled with His tag.

Purpose: Recombinant Mouse SECTM1A (C-6His)

Sequence: Gln28-Thr165

Characteristics: Recombinant Mouse Secreted And Transmembrane Protein 1A is produced by our Mammalian expression system and the target gene encoding Gln28-Thr165 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SECTM1A (Secreted and Transmembrane 1A (SECTM1A))

Alternative Name: SECTM1A

Background:

Background: SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect human SECTM1 expression, and it is thought to be an interferon early response gene. Mouse SECTM1A cDNA encodes a signal sequence, an extracellular domain with four potential N linked glycosylation sites, a transmembrane sequence, and a very short (approximately 6 aa) cytoplasmic sequence. SECTM1 proteins from human and mouse show species specific binding of CD7 and co stimulation of T cells, including enhancement of CD3 induced proliferation.

Synonym: SECTM1A, Sectm1a

Molecular Weight: 16.2 kDa

UniProt: A2ABP9