SEMA4D/CD100 Protein (Fc Tag)
Quick Overview for SEMA4D/CD100 Protein (Fc Tag) (ABIN7321134)
Target
See all SEMA4D/CD100 (SEMA4D) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This SEMA4D/CD100 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rat Semaphorin 4D/SEMA4D/CD100 Protein (Fc Tag)
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Sequence
- Met1-Met712
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Characteristics
- A DNA sequence encoding the rat SEMA4D (Met1-Met712) was expressed with the Fc region of human IgG1 at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
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Alternative Name
- Semaphorin 4D/SEMA4D/CD100
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Background
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Background: Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system, Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
Synonym: SEMA4D
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Molecular Weight
- 103.4 kDa
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NCBI Accession
- NP_001164034
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Pathways
- Regulation of Cell Size
Target
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