SMAD5 Protein
Quick Overview for SMAD5 Protein (ABIN7320167)
Target
See all SMAD5 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Mouse Smad5 Protein
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Sequence
- Thr2-Ser465
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Characteristics
- A DNA sequence encoding the mouse SMAD5 (P97454) (Thr2-Ser465) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 186-465) protein (His-IF2DI Tag)
SMAD5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
SMAD, Mothers Against DPP Homolog 5 (SMAD5) protein (GST tag,His tag)SMAD5 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 1-465) protein (GST tag)SMAD5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM Nacl,10 % glycerol, pH 8.0
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
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Alternative Name
- Smad5
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Background
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Background: SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.
Synonym: 1110051M15Rik,AI451355,Dwf-C,Madh5,MusMLP
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Molecular Weight
- 52.2 kDa
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UniProt
- P97454
Target
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