SULT1E1 Protein (His tag)
Quick Overview for SULT1E1 Protein (His tag) (ABIN7317598)
Target
See all SULT1E1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This SULT1E1 protein is labelled with His tag.
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Purpose
- Recombinant Human SULT1E1/ST1E1 Protein (His Tag)
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Sequence
- Asn 2-Ile 294
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Characteristics
- A DNA sequence encoding the human SULT1E1 (NP_005411.1) (Asn 2-Ile 294) was expressed, with a polyhistidine tag at the N-terminus.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile 20 mM Tris 0.5M NaCl, 20 % glycerol, pH 8.0
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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Alternative Name
- SULT1E1/ST1E1
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Background
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Background: Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme which belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradiol. SULT1E1 maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. SULT1E1 also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. SULT1E1 is a key enzyme in estrogen homeostasis. It plays a central role in the prevention and development of human disease.
Synonym: EST;EST-1;MGC34459;ST1E1;STE
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Molecular Weight
- 36 kDa
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NCBI Accession
- NP_005411
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Pathways
- Steroid Hormone Biosynthesis
Target
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