Syndecan 1 Protein (SDC1) (Fc Tag)
Quick Overview for Syndecan 1 Protein (SDC1) (Fc Tag) (ABIN7319451)
Target
See all Syndecan 1 (SDC1) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Syndecan 1 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human Syndecan-1/SDC1 Protein (Fc Tag)
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Sequence
- Gln18-Glu251(Leu136Gln)
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Characteristics
- Recombinant Human Syndecan-1 is produced by our Mammalian expression system and the target gene encoding Gln18-Glu251(Leu136Gln) is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Syndecan 1 (SDC1)
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Alternative Name
- Syndecan-1/SDC1
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Background
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Background: Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence, and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
Synonym: Syndecan-1, SYND1, CD138, SDC1, SDC
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Molecular Weight
- 51 kDa
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UniProt
- P18827
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Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
Target
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