Syndecan 1 Protein (SDC1) (AA 23-254) (His tag)

Catalog No. ABIN7275677

Product Details

Target: Syndecan 1 (SDC1)

Protein Type: Recombinant

Protein Characteristics: AA 23-254

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Syndecan 1 protein is labelled with His tag.

Purpose: Human Syndecan-1 Protein

Sequence: Gln23-Gly254

Characteristics: Recombinant Human Syndecan-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Gly254.

Purity: > 95 % as determined by Tris-Bis PAGE

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human Syndecan-1, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Syndecan-1 Antibody, hFc Tag with the EC50 of 28.2ng/ml determined by ELISA. See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Syndecan 1 (SDC1)

Alternative Name: Syndecan-1 (SDC1 Products)

Synonyms: CG10497 Protein, CT27296 Protein, Dmel\\CG10497 Protein, Dsyn Protein, Syd Protein, Syn Protein, dSdc Protein, l(2)10608 Protein, sdc Protein, syd Protein, syn Protein, Syn1 Protein, cd138 Protein, synd1 Protein, xSyn1 Protein, syndecan1 Protein, Syndecan-1 Protein, XSyndecan-1 Protein, SDC1 Protein, CD138 Protein, SDC Protein, SYND1 Protein, syndecan Protein, AA408134 Protein, AA409076 Protein, Sstn Protein, Synd Protein, Synd1 Protein, syn-1 Protein, HSPG Protein, SYNDECA Protein, Syndecan Protein, Syndecan Protein, syndecan 1 Protein, Sdc Protein, sdc1 Protein, SDC1 Protein, Sdc1 Protein

Background: Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver.

Molecular Weight: 25 kDa. Due to glycosylation, the protein migrates to 50-80 kDa based on Tris-Bis PAGE result.

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism