TSPAN1 Protein (Fc Tag)
Quick Overview for TSPAN1 Protein (Fc Tag) (ABIN7317314)
Target
See all TSPAN1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This TSPAN1 protein is labelled with Fc Tag.
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Purpose
- Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag)
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Sequence
- Tyr110-Asn211
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Characteristics
- A DNA sequence encoding the human TSPAN1 (O60635)(Tyr110-Asn211) was expressed with the Fc region of rabbit IgG at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Tetraspanin 1 (TSPAN1) (AA 1-241) protein (His tag)
custom-made TSPAN1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 1 (TSPAN1) (AA 1-240) protein (His tag)custom-made TSPAN1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 1 (TSPAN1) (AA 110-211) protein (GST tag)TSPAN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Tetraspanin 1 (TSPAN1) (AA 1-241) protein (GST tag)TSPAN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from sterile PBS, pH 7.4
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TSPAN1 (Tetraspanin 1 (TSPAN1))
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Alternative Name
- TSPAN1
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Background
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Background: TSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone, in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.
Synonym: NET1,TM4C,TM4SF,TSPAN1
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Molecular Weight
- 39.1 kDa
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UniProt
- O60635
Target
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