TXN2 Protein (His tag)
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- Target See all TXN2 Proteins
- TXN2 (Thioredoxin 2 (TXN2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TXN2 protein is labelled with His tag.
- Purpose
- Recombinant Human Thioredoxin-2/TXN2 Protein (His Tag)
- Sequence
- Thr60-Gly166
- Characteristics
- Recombinant Human Thioredoxin-2 is produced by our E.coli expression system and the target gene encoding Thr60-Gly166 is expressed with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TXN2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TXN2 (Thioredoxin 2 (TXN2))
- Alternative Name
- Thioredoxin-2/TXN2 (TXN2 Products)
- Background
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Background: Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.
Synonym: Thioredoxin Mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2
- Molecular Weight
- 12.0 kDa
- UniProt
- Q99757
- Pathways
- Cell RedoxHomeostasis
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