Toxin B Protein

Catalog No. ABIN7321014

This Recombinant Toxin B protein is produced in Escherichia coli (E. coli).

Quick Overview for Toxin B Protein (ABIN7321014)

Target: Toxin B

Protein Type: Recombinant

Origin: Vibrio cholerae

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Vibrio cholerae Toxin B Protein

Sequence: Thr22-Asn124

Characteristics: Recombinant Vibriocholerae Toxin B is produced by our E.coli expression system and the target gene encoding Thr22-Asn124 is expressed.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 200 mM NaCl, pH 8.0.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Toxin B

Background:

Background: Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.

Synonym: Cholera enterotoxin subunit B,Cholera enterotoxin B chain,Cholera enterotoxin gamma chain,Choleragenoid,ctxB,toxB

Molecular Weight: 11.8 kDa

UniProt: P01556