TGFB2 Protein
Quick Overview for TGFB2 Protein (ABIN7319106)
Target
See all TGFB2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human TGFB2 Protein (Active)
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Sequence
- Ala303-Ser414
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Characteristics
- Recombinant Human Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 0.3-1.5 ng/ml.
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Transforming Growth Factor, beta 2 (TGFB2) (AA 303-414) protein (AVI tag,Biotin)
TGFB2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 2 (TGFB2) (Active) proteinTGFB2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Transforming Growth Factor, beta 2 (TGFB2) (AA 1-414) protein (GST tag)TGFB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
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Alternative Name
- TGFB2
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Background
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Background: Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
Synonym: Transforming growth factor beta-2,TGFB2,Polyergin,G-TSF,Glioblastoma-derived T-cell suppressor factor,Cetermin,BSC-1 cell growth inhibitor,TGF-beta-2
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Molecular Weight
- 12.7 kDa
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UniProt
- P61812
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Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Target
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